Synonyms :  CTLA-4 
Host :  CHO cells 
Sequence :  The extracellular domain ofhuman CD152[CTLA-4](NP_005205.2)(Ala37-Ser160) is fused to the N-terminus of the Fc region of a mutant human IgG1 
Molecular Mass:  39 KDa (monomer) 
Non-lytic:  Acts as a long lasting fusion protein which only binds to the receptor. Mutations to the complement(C1q) and FcgRI binding sites of the IgGs Fc fragment render the fusion proteins incapable ofantibody directed cytotoxicity (ADCC) and complement directed cytotoxicity (CDC). 
Purity :  >98%，by SDS-PAGE under reducing conditions.  
Endotoxin Content :  <0.06 EU/μg as determined by LAL test. 

Activity :  Measured by its ability to inhibit IL-2 secretion by stimulated Jurkat human acute T cell leukemia cells.  
Formulation :  Lyophilized from 0.2μm-filtered solution in PBS. 
Reconstitution :  Reconstitute at 100μg/ml in sterile PBS. 
Use / Stability :  
Stable for at least 1 year after receipt when stored at -20℃. Working aliquots are stable for up to 3 months when stored at -20℃. 
Avoid freeze/thaw cycles.